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작성자 Andreas
댓글 0건 조회 487회 작성일 23-06-01 01:08

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Railroad Lawsuits - aplastic anemia [sites.google.Com]

Railroad workers who use solvents like benzene regular basis have an increased risk for developing aplastic anemia. These solvents are used to clean locomotive engines and other railroad equipment.

Typically, the disease is diagnosed by obtaining blood from a vein and conducting specific tests in the lab. The only way to treat the disease is with the transplant of bone marrow (stem cells).

Causes

The bone Marrow is a spongy, spongy substance in the majority of the bones of the body, such as the hips, spine and rib cage. Hematopoietic stem cell cells are found there and may give birth to other blood-forming cells. If acquired aplastic aemia occurs the stem cells are unable to produce enough white blood cells, platelets or red blood cells.

Signs of fatigue include breathing problems, unintentional or prolonged bleeding or infection. Aplastic anemia can cause problems with the kidneys, lungs and heart. If left untreated, it could be fatal.

Treatment is contingent on the severity of aplasticanemia. The mild cases that do not exhibit symptoms typically require only monitoring by a doctor. The most severe cases of low blood counts that require hospitalization might be required. They can be treated using blood transfusions and medications like erythropoietin, which help the bone marrow to produce more red blood cells. Infections pose a serious issue for patients suffering from aplastic angiopathy and may require antibiotics or antifungal medication. Sometimes, a central vein is used to deliver infused medicine, such as iron and Folic acids.

Signs and symptoms

Due to their low white blood cell count, aplastic anemia patients face an increased risk of developing severe infections. They are often required to avoid large crowds and sick people. Iron can hinder the body's ability in producing new red blood cells or platelets. In the most severe situations, blood is circulated to provide healthy platelets and red blood cells. In addition, they may receive medications to control their immune system's malfunction and drugs that stimulate bone marrow to produce more stem cells.

Although doctors aren't able to determine the reason for most cases of aplastic anemia, some patients go into spontaneous remission. This is a situation where mild symptoms go away themselves. Aplastic Anemia is characterized as a persistent fever and excessive bleeding. It can be accompanied by absence of platelets. Railroad workers who work around organic solvents like benzene or Nitrates, for example, locomotive machinists or railroad car department employees are at a greater risk of developing aplastic nephropathy because of the toxic chemicals they employ to clean their cars and engines.

Diagnosis

A complete blood count is the initial step to identify aplastic anemia. This includes the count of red, white, and platelet-producing cells. A CBC can also reveal whether the bone marrow is producing blood cells in the normal way and is healthy. A low reticulocyte number may indicate that bone marrow does not make new red blood cells.

A doctor will want to examine the type of cancer that is present in your blood as well as other factors creating the aplastic brain encephalomyelitis. Blood tests and genetic testing can aid in this. You can also request a chest x-ray and computed tomography (CT) scan to see whether you have larger lymph nodes.

Aplastic anemia is more common in those who have been exposed to toxic chemicals. This includes workers in the oilfield, refinery and gas stations who work with benzene, as well those working in the paints, solvents greases, degreasers, glues, and rubber industries. A background of chemotherapy or radiation treatment, or autoimmune disorders such as hepatitis or lupus, or infections that are viral like Epstein Barr virus or HIV can also increase your risk of being affected by this disease.

Treatment

The first step is to consult a health professional who will try to treat the underlying condition that could be causing the illness or causing it to get worse. This could include reducing exposure to a toxic chemical or a virus, or taking medications to treat the immune system's malfunction for example, anthymocyte-globulin (ATG) and the cyclosporine.

Blood cells, including red blood cells and platelets, are often given by transfusion through a tube placed in a blood vessel. This can help to stabilize symptoms, but it does not treat the illness.

The most promising treatment for severe aplasticanemia is bone marrow transplant, but it is only feasible for patients with a matching donor -- typically one of their siblings. This procedure is not recommended for women who are pregnant because of the risk of toxicity of the embryo.

Aplastic anemia is caused by certain chemicals, particularly the chemical benzene that is found in diesel fuel and gasoline. Locomotive conductors as well as locomotive engineers and yard workers are at a higher risk of developing this disease if they are regularly exposed to benzene. Benzene can also be found in solvents, paints, and degreasers in railroad workplaces.

Prognosis

Aplastic anemia can lead to other serious illnesses and complications, including death. It is caused by damage to blood stem cells. These are stem cells of the blood that transform into white blood, Aplastic anemia red blood and platelets.

A bone marrow transfusion gives the patient healthy cells to replace damaged ones. This is the only treatment that can cure aplastic anemia. Unfortunately, not every patient is able to find a bone marrow match. Immunosuppressive therapy could improve the prognosis for these patients.

The exposure to chemicals in the workplace, like benzene which is present in petroleum-based products such as solvents, degreasers and gasolines, paint thinners, and other liquids could increase the chance of developing this condition. These chemicals are used by numerous workers such as mechanics, railroad employees, plumbers and oilfield and refinery workers. Pressmen, tanker trucks drivers, gas station attendants and drillers.

Certain patients have a mild form of the disease that goes away on its own (goes into an era of remission). This kind of aplastic anemia is called idiopathic aplastic anemia.

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